Products for Research Use Only

GSK591

CAT: 0013-GTR19168019-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19168019-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GSK591 (EPZ015866) is a potent and selective PRMT5 inhibitor with an IC50 of 11 nM. It is a valuable chemical probe for investigating PRMT5 biology in cancer research, demonstrating utility in both in vitro cellular assays and in vivo preclinical models of hematologic malignancies.
CAS Number
1616391-87-7
Product Name Alternative
HistoneMethyltransferase, Histone Methyltransferase, Inhibitor, GSK591, GSK-591, GSK 591, GSK 3203591, GSK3203591, GSK-3203591, EPZ015866, EPZ-015866, EPZ 015866, inhibit, PRMT5
Field of Research
Epigenetics & Chromatin
Purity
99.09% (May vary between batches)
Solubility
DMSO:60 mg/mL (157.7 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.26 mM)
Smiles
O[C@@H] (CNC (=O) c1ccnc (NC2CCC2) c1) CN1CCc2ccccc2C1
Molecular Formula
C22H28N4O2
Molecular Weight
380.48
Storage Conditions
-20°C
Notes
For research use only.