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PF-4989216

CAT: 0013-GTR19167939-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19167939-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PF-4989216 is a potent and selective PI3K inhibitor, exhibiting IC50 values of 2 nM (p110α), 1 nM (p110δ), 65 nM (p110γ), 142 nM (p110β), and 110 nM (VPS34) . This tool compound is used in biochemical and cellular assays to investigate PI3K signaling pathways in oncology and immunology research contexts.
CAS Number
1276553-09-3
Product Name Alternative
Apoptosis, Inhibitor, inhibit, p110β, p110γ, p110δ, p110α, PF 4989216, PF4989216, PF-4989216, Phosphoinositide 3-kinase, PI3K, Vps34
Field of Research
Cell Biology, Signal Transduction
Purity
99.53% (May vary between batches)
Solubility
Ethanol:7 mg/mL (18.4 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:71 mg/mL (186.65 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.26 mM)
Smiles
Fc1cc (ccc1-c1c (sc (N2CCOCC2) c1C#N) -c1ncn[nH]1) C#N
Molecular Formula
C18H13FN6OS
Molecular Weight
380.4
Storage Conditions
-20°C
Notes
For research use only.

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B5948-10PF-4989216
A12889-100PF-4989216 100mg
A12889-50PF-4989216 50mg
A12889-5PF-4989216 5mg
A12889-25PF-4989216 25mg
A12889-2PF-4989216 2mg

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