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BTdCPU

CAT: 0013-GTR19167513-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19167513-01Size:1 mg
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Description
BTdCPU is a potent small molecule activator of the heme-regulated eIF2α kinase (HRI), leading to increased eIF2α phosphorylation and apoptosis induction in resistant cells. It is a valuable research tool for studying the integrated stress response, protein synthesis regulation, and overcoming therapy resistance in both cellular and animal models.
CAS Number
1257423-87-2
Product Name Alternative
Phosphatase, eIF-2α, Inhibitor, inhibit, BTdCPU, Apoptosis
Field of Research
Cell Biology, Metabolism Research
Purity
98.00% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (14.74 mM) ; DMSO:250 mg/mL (737.03 mM)
Smiles
Clc1ccc (NC (=O) Nc2ccc3nnsc3c2) cc1Cl
Molecular Formula
C13H8Cl2N4OS
Molecular Weight
339.2
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

1-(Benzo[d][1,2,3]thiadiazol-6-yl)-3-(3,4-dichlorophenyl)urea
CAS Number1257423-87-2
PubChem CID49787174
IUPAC Name1-(1,2,3-benzothiadiazol-6-yl)-3-(3,4-dichlorophenyl)urea
Molecular FormulaC13H8Cl2N4OS
Molecular Weight339.2
XLogP3.7
Topological Polar Surface Area95.2
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count2
Heavy Atom Count21
Formal Charge0
Complexity389
SMILES
C1=CC2=C(C=C1NC(=O)NC3=CC(=C(C=C3)Cl)Cl)SN=N2
InChI
InChI=1S/C13H8Cl2N4OS/c14-9-3-1-7(5-10(9)15)16-13(20)17-8-2-4-11-12(6-8)21-19-18-11/h1-6H,(H2,16,17,20)
InChIKey
NUUSUAWULNXMGF-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 1-(Benzo[d][1,2,3]thiadiazol-6-yl)-3-(3,4-dichlorophenyl)urea
CAS: 1257423-87-2
CID: 49787174
Formula: C13H8Cl2N4OS
MW: 339.2
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight339.2
XLogP33.7
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count2
Exact Mass337.9795875
Monoisotopic Mass337.9795875
Topological Polar Surface Area95.2 Ų
Heavy Atom Count21
Formal Charge0
Complexity389
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
M20636-01BTdCPU
217337-01EIF2-GTP-tRNAiMet Ternary Complex Inhibitor, BTdCPU (N, N'-diarylurea; translation Initiation Tenrary Complex Inhibitor, 1- (benzo[d][1,2,3]thiadiazol-6-yl) -3- (3,4-dichlorophenyl) urea, BTdCPU, Heme-regulated Inhibitor Kinase Activator, BTdCPU)

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