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CNQX

CAT: 0013-GTR19167492-02Size: 1 ml x 10 mM (in DMSO)Dry Ice: NoHazardous: No
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CAT#:0013-GTR19167492-02Size:1 ml x 10 mM (in DMSO)
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Description
CNQX (FG9065) is a selective competitive antagonist for AMPA and kainate subtypes of ionotropic glutamate receptors, exhibiting IC50 values of 0.3 μM and 1.5 μM, respectively. It is widely used in neuroscience research to study excitatory synaptic transmission, neuronal excitability, and mechanisms of neuroprotection in both in vitro and in vivo experimental models.
CAS Number
115066-14-3
Product Name Alternative
CNQX, AMPA, non-NMDA, kainate, inhibit, Ionotropic glutamate receptors, FG9065, FG-9065, FG 9065, fear-potentiated, Inhibitor, iGluR, startle
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
≥95% (May vary between batches)
Solubility
DMSO:20 mg/mL (86.15 mM)
Smiles
[O-][N+] (=O) c1cc2[nH]c (=O) c (=O) [nH]c2cc1C#N
Molecular Formula
C9H4N4O4
Molecular Weight
232.15
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

6-Cyano-7-nitroquinoxaline-2,3-dione

6-Cyano-7-nitroquinoxaline-2,3-dione is a quinoxaline derivative.

CAS Number115066-14-3
PubChem CID3721046
IUPAC Name7-nitro-2,3-dioxo-1,4-dihydroquinoxaline-6-carbonitrile
Molecular FormulaC9H4N4O4
Molecular Weight232.15
XLogP0
Topological Polar Surface Area128
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count0
Heavy Atom Count17
Formal Charge0
Complexity434
SMILES
C1=C(C(=CC2=C1NC(=O)C(=O)N2)[N+](=O)[O-])C#N
InChI
InChI=1S/C9H4N4O4/c10-3-4-1-5-6(2-7(4)13(16)17)12-9(15)8(14)11-5/h1-2H,(H,11,14)(H,12,15)
InChIKey
RPXVIAFEQBNEAX-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 6-Cyano-7-nitroquinoxaline-2,3-dione
CAS: 115066-14-3
CID: 3721046
Formula: C9H4N4O4
MW: 232.15
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight232.15
XLogP30
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count0
Exact Mass232.02325462
Monoisotopic Mass232.02325462
Topological Polar Surface Area128 Ų
Heavy Atom Count17
Formal Charge0
Complexity434
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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