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AZD7325

CAT: 0013-GTR19167471-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19167471-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AZD7325 is a selective modulator of GABA-A receptors containing α2 and α3 subunits. It is utilized in preclinical research to investigate anxiolytic and analgesic mechanisms, with studies conducted in both in vitro binding assays and in vivo animal models.
CAS Number
942437-37-8
Product Name Alternative
Dravet, Cytochrome P450, CYPs, CYP1A2, anxiety, AZD 7325, AZD7325, AZD-7325, Inhibitor, effect, GABAReceptor, GABA, GABA Receptor, Gamma-aminobutyric acid Receptor, inhibit, modulator, PAM, syndrome, sedative, γ-Aminobutyric acid Receptor
Field of Research
Metabolism Research, Neuroscience, Pharmacology & Drug Discovery
Purity
99.83% (May vary between batches)
Solubility
DMSO:9 mg/mL (25.4 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.82 mM)
Smiles
CCCNC (=O) c1nnc2c (cccc2c1N) -c1c (F) cccc1OC
Molecular Formula
C19H19FN4O2
Molecular Weight
354.38
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Azd-7325

AZD7325 is a high affinity, selective modulator of the GABAA receptor system.

CAS Number942437-37-8
PubChem CID23581869
IUPAC Name4-amino-8-(2-fluoro-6-methoxyphenyl)-N-propylcinnoline-3-carboxamide
Molecular FormulaC19H19FN4O2
Molecular Weight354.4
XLogP3.3
Topological Polar Surface Area90.1
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count5
Heavy Atom Count26
Formal Charge0
Complexity480
SMILES
CCCNC(=O)C1=NN=C2C(=C1N)C=CC=C2C3=C(C=CC=C3F)OC
InChI
InChI=1S/C19H19FN4O2/c1-3-10-22-19(25)18-16(21)12-7-4-6-11(17(12)23-24-18)15-13(20)8-5-9-14(15)26-2/h4-9H,3,10H2,1-2H3,(H2,21,23)(H,22,25)
InChIKey
KYDURMHFWXCKMW-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Azd-7325
CAS: 942437-37-8
CID: 23581869
Formula: C19H19FN4O2
MW: 354.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight354.4
XLogP33.3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count5
Exact Mass354.14920402
Monoisotopic Mass354.14920402
Topological Polar Surface Area90.1 Ų
Heavy Atom Count26
Formal Charge0
Complexity480
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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HY-111052-01AZD7325
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