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Voxelotor

CAT: 0013-GTR19166469-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19166469-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Voxelotor (GBT 440) is a small molecule therapeutic agent for sickle cell disease research that inhibits hemoglobin S polymerization by covalently binding to the alpha chain. It functions as a hemoglobin stabilizer and a cytochrome P450 3A4 inhibitor, with applications in both in vitro mechanistic studies and in vivo preclinical models.
CAS Number
1446321-46-5
Product Name Alternative
Polymerization, inhibit, GBT 440, GBT440, GBT-440, Inhibitor, HbS, haemoglobin, disease, cell, sickle, sickle hemoglobin (HbS), SCD, voxelotor
Field of Research
Pharmacology & Drug Discovery
Purity
99.87% (May vary between batches)
Solubility
DMSO:79 mg/mL (234.16 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.93 mM)
Smiles
CC (C) n1nccc1-c1ncccc1COc1cccc (O) c1C=O
Molecular Formula
C19H19N3O3
Molecular Weight
337.37
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
T7581-01Voxelotor
HY-18681SVoxelotor-d6
A20863-100Voxelotor 100mg
A20863-50Voxelotor 50mg
A20863-5Voxelotor 5mg
CS-O-42054Voxelotor D6
HY-18681R-01Voxelotor (Standard)
CS-SN-00088Voxelotor-D7
A20863-10Voxelotor 10mg
CS-BL-00160Voxelotor Impurity 2

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