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Naphthazarin

CAT: 0013-GTR19165955-05Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19165955-05Size:200 mg
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Description
Naphthazarin is a multi-mechanism small molecule that induces apoptosis and exerts anti-tumor effects through oxidative stress, AIF-mediated apoptosis, microtubule disruption, and lysosomal interference. It is used in cancer research, demonstrating activity in both in vitro cell culture and in vivo animal models.
CAS Number
475-38-7
Product Name Alternative
DHNQ, anti-tumor, Apoptosis, apoptosis, 5,8-Dihydroxy-1,4-naphthoquinone, AIF, Inhibitor, inhibit, Naturally, Naphthazarin, lysosomal, p53-dependent, microtubules, mitochondrial, oxidative, p21, stress
Field of Research
Cell Biology, Signal Transduction
Purity
97.10% (May vary between batches)
Solubility
DMSO:10 mg/mL (52.59 mM)
Smiles
Oc1ccc (O) c2C (=O) C=CC (=O) c12
Molecular Formula
C10H6O4
Molecular Weight
190.15
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Naphthazarin

Naphthazarin is a naphthoquinone that is 1,4-naphthoquinone in which the hydrogens at positions 5 and 8 are replaced by hydroxy groups. It has a role as a geroprotector, an acaricide, an antibacterial agent, an antineoplastic agent, an apoptosis inducer and a plant metabolite.

CAS Number475-38-7
PubChem CID10141
IUPAC Name5,8-dihydroxynaphthalene-1,4-dione
Molecular FormulaC10H6O4
Molecular Weight190.15
XLogP1.8
Topological Polar Surface Area74.6
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count0
Heavy Atom Count14
Formal Charge0
Complexity277
SMILES
C1=CC(=C2C(=O)C=CC(=O)C2=C1O)O
InChI
InChI=1S/C10H6O4/c11-5-1-2-6(12)10-8(14)4-3-7(13)9(5)10/h1-4,11-12H
InChIKey
RQNVIKXOOKXAJQ-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Naphthazarin
CAS: 475-38-7
CID: 10141
Formula: C10H6O4
MW: 190.15
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight190.15
XLogP31.8
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count0
Exact Mass190.02660867
Monoisotopic Mass190.02660867
Topological Polar Surface Area74.6 Ų
Heavy Atom Count14
Formal Charge0
Complexity277
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
BA3000-250Naphthazarin
HY-N7526R-01Naphthazarin (Standard)

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