Products for Research Use Only
RegisterLogin

TKIM

CAT: 0013-GTR19165938-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19165938-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
TKIM is a small molecule inhibitor that selectively targets the intermediate (IM) state of the TREK-1 potassium channel (KCNK2) . It serves as a valuable research tool for investigating TREK-1's role in pain perception, depression, and neuroprotection in both cellular and animal models.
CAS Number
326921-25-9
Product Name Alternative
TREK-1, TKIM, Potassium Channel, PotassiumChannel
Field of Research
Pharmacology & Drug Discovery
Purity
99.30% (May vary between batches)
Solubility
DMSO:30 mg/mL (80.68 mM)
Smiles
S (CC (NNC (=O) C1=CC=C (Cl) C=C1) =O) C2=NC3=C (C=C2) C=CC=C3
Molecular Formula
C18H14ClN3O2S
Molecular Weight
371.84
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

4-chloro-N'-(2-quinolin-2-ylsulfanylacetyl)benzohydrazide
CAS Number326921-25-9
PubChem CID3115384
IUPAC Name4-chloro-N'-(2-quinolin-2-ylsulfanylacetyl)benzohydrazide
Molecular FormulaC18H14ClN3O2S
Molecular Weight371.8
XLogP4.2
Topological Polar Surface Area96.4
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count4
Heavy Atom Count25
Formal Charge0
Complexity471
SMILES
C1=CC=C2C(=C1)C=CC(=N2)SCC(=O)NNC(=O)C3=CC=C(C=C3)Cl
InChI
InChI=1S/C18H14ClN3O2S/c19-14-8-5-13(6-9-14)18(24)22-21-16(23)11-25-17-10-7-12-3-1-2-4-15(12)20-17/h1-10H,11H2,(H,21,23)(H,22,24)
InChIKey
BWTKIGGLLXUFSV-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 4-chloro-N'-(2-quinolin-2-ylsulfanylacetyl)benzohydrazide
CAS: 326921-25-9
CID: 3115384
Formula: C18H14ClN3O2S
MW: 371.8
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight371.8
XLogP34.2
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count4
Exact Mass371.0495256
Monoisotopic Mass371.0495256
Topological Polar Surface Area96.4 Ų
Heavy Atom Count25
Formal Charge0
Complexity471
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19069642-01Tkip
GTR17961051TKI1 Antibody
GTR19206068-01Tarlox-TKI

Alternative Products

CatalogName
MBS5759478TKIM

Popular Products