DS-1205

CAT: 0013-GTR19165783-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19165783-01Size:1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

DS-1205 is a highly potent and selective AXL kinase inhibitor (IC50 = 1.3 nM), with additional activity against MER, MET, and TRKA kinases. This small molecule has demonstrated efficacy in suppressing cell migration in vitro and impeding tumor growth in animal models, supporting its research use in oncology and metastasis studies.

CAS Number

1855860-24-0

Product Name Alternative

C-Met/HGFR, DS 1205, DS1205, DS-1205, DS-1205b, AXL, Axl, Inhibitor, Mer, NIH3T3, MET, migration, kinase, inhibit, Tropomyosin related kinase receptor, TRKA, Trk Receptor, Tyro3, tumor, TAM Receptor, TAMReceptor

Field of Research

Signal Transduction

Purity

99.28% (May vary between batches)

Solubility

DMSO:45 mg/mL (61.16 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (2.72 mM)

Smiles

COc1cc (ccc1OC[C@H]1COCCO1) -c1cnc (N) c (c1) -c1ccc (NC (=O) c2cn (CC3CCOCC3) cc (-c3ccc (C) cn3) c2=O) cc1F

Molecular Formula

C41H42FN5O7

Molecular Weight

735.8

Storage Conditions

-20°C

Notes

For research use only.

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T9123-01	DS-1205
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T9901A-064-01	LIV-1205
B2509-5	CPI-1205
MBS5812921	ZBH-1205

DS-1205

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