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THIQ

CAT: 0013-GTR19166035-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19166035-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
THIQ is a potent and selective agonist of the melanocortin-4 receptor (MC4R), demonstrating high affinity with IC50 values of 1.2 nM for human and 0.6 nM for rat receptors. This small molecule is a valuable research tool for studying energy homeostasis and obesity in both in vitro binding assays and in vivo metabolic studies.
CAS Number
312637-48-2
Product Name Alternative
Affinity, activity, Inhibitor, MC Receptor, melanocortin, Melanocortin Receptor, melanocortin-4 receptor (MC4R), MelanocortinReceptor, erectile, eliciting, mutant, inhibit, selective, THIQ
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
95.28% (May vary between batches)
Solubility
DMSO:245 mg/mL (415.84 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (8.49 mM)
Smiles
ClC1=CC=C (C[C@@H] (NC (=O) [C@H]2CC3=CC=CC=C3CN2) C (=O) N2CCC (CN3C=NC=N3) (CC2) C2CCCCC2) C=C1
Molecular Formula
C33H41ClN6O2
Molecular Weight
589.17
Storage Conditions
-20°C
Notes
For research use only.

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