Products for Research Use Only
RegisterLogin

Idasanutlin

CAT: 0013-GTR19164233-01Size: 200 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19164233-01Size:200 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Idasanutlin (RG-7388) is a potent and selective p53-MDM2 inhibitor with IC50 of 6 nM. (In Vitro) :Idasanutlin (RG7388) inhibits cell proliferation with IC50 of 30 nM, and induces dose-dependent p53 stabilization, cell cycle arrest, as well as cell apoptosis in cancer cells expressing wild-type p53. Idasanutlin (RG7388) (300 nM or 1.8 μM) induces apoptosis in SJSA osteosarcoma cells. (In Vivo) :Idasanutlin (RG7388, 25 mg/kg p.o.) results in tumor growth inhibition and regression, in the mouse SJSA human osteosarcoma xenograft model. Idasanutlin (RG7388) induces induction of apoptosis and antiproliferation, in the SJSA xenograft model.
CAS Number
1229705-06-9
Product Name Alternative
RG-7388
Purity
>98% (HPLC)
Solubility
DMSO:100 mg/mL (162.21 mM) ; Ethanol:8 mg/mL warmed (12.97 mM) ; Water:<1 mg/mL (<1 mM)
Smiles
O=C (O) C1=CC=C (NC ([C@@H]2N[C@@H] (CC (C) (C) C) [C@] (C#N) (C3=CC=C (Cl) C=C3F) [C@H]2C4=CC=CC (Cl) =C4F) =O) C (OC) =C1
Molecular Formula
C31H29Cl2F2N3O4
Molecular Weight
616.48
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
4- ((2R,3S,4R,5S) -3- (3-chloro-2-fluorophenyl) -4- (4-chloro-2-fluorophenyl) -4-cyano-5-neopentylpyrrolidine-2-carboxamido) -3-methoxybenzoic acid.

Alternative Products

CatalogName
HY-15676-01Idasanutlin
S7205-1gIdasanutlin (RG7388)
HY-15676A-01Idasanutlin (enantiomer)
A14211-25Idasanutlin 25mg
HY-15676R-01Idasanutlin (Standard)
A14211-5Idasanutlin 5mg
A14211-10Idasanutlin 10mg

Popular Products