Products for Research Use Only

BP-1-102

CAT: 0013-GTR19163827-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19163827-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
An orally bioavailable, small-molecule inhibitor of STAT3 with Kd of 504 nM; blocks Stat3-pTyr peptide interactions and Stat3 activation at 4-6.8 uM, and selectively inhibits growth, survival, migration, and invasion of Stat3-dependent tumor cells; suppresses the expression of c-Myc, Cyclin D1, Bcl-xL, Survivin, VEGF, and KLF8, blocks Stat3-NF-κB cross-talk, and enhances E-cadherin expression; inhibits growth of human breast and lung tumor xenografts.
CAS Number
1334493-07-0
Product Name Alternative
BP-1-102 | BP1-102 | BP 1-102 | BP1102
Field of Research
Cancer Biology
Purity
>98% (HPLC)
Solubility
DMSO: ≥ 33 mg/mL
Smiles
O=C (O) C1=CC=C (N (CC2=CC=C (C3CCCCC3) C=C2) C (CN (C) S (=O) (C4=C (F) C (F) =C (F) C (F) =C4F) =O) =O) C=C1O
Molecular Formula
C29H27F5N2O6S
Molecular Weight
626.5915
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Benzoic acid, 4-[[ (4-cyclohexylphenyl) methyl][2-[methyl[ (2,3,4,5,6-pentafluorophenyl) sulfonyl]amino]acetyl]amino]-2-hydroxy-

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