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Flavokawain B

CAT: 0013-GTR19163481-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0013-GTR19163481-01Size:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Flavokawain B is a natural chalcone that can induce apoptosis in androgen receptor-negative, hormone-refractory prostate cancer cell lines (IC50=3-50 uM), via up-regulation of death-receptor 5 and Bim expression; induces apoptosis in human myeloid leukemic cells by modifying NF-κB, possesses potential anti-inflammation and anti-cancer activities; also exhibits significant inhibition of the neurogenic nociceptive induced by intraplantar injections of glutamate and capsaicin in mice.
CAS Number
1775-97-9
Product Name Alternative
Flavokawain B | Flavokawain-B | FlavokawainB
Purity
>98% (HPLC)
Solubility
Chloroform: Soluble Dichloromethane: SolubleEthyl Acetate: SolubleAcetone: SolubleDMSO: 38 mg/mL (133.7 mM) (< 1 mg/ml refers to the product slightly soluble or insoluble)
Smiles
O=C (C1=C (OC) C=C (OC) C=C1O) /C=C/C2=CC=CC=C2
Molecular Formula
C17H16O4
Molecular Weight
284.311
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
2-Propen-1-one, 1- (2-hydroxy-4,6-dimethoxyphenyl) -3-phenyl-, (E) -

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