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Flavokawain A

CAT: 0013-GTR19159769-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19159769-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Flavokawain A has anti-tumor activity, such as inhibits growth of bladder tumor cells in a nude mice model , prevents the recurrence and progression of non-muscle-invasive urothelial cell carcinoma. Flavokawain A can significantly reduce the expression of CDK1-inhibitory kinases, Myt1 and Wee1, and cause cyclin B1 protein accumulation leading to CDK1 activation in T24 cells. Flavokawain A may exert anti-inflammatory responses by suppressing LPS-induced expression of pro-inflammatory mediators via blockage of NF-κB-AP-1-JNK/p38 MAPK signaling pathways in the murine macrophages.
CAS Number
3420-72-2
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 100 mg/mL (318.14 mM)
Smiles
COC1=CC=C (C=C1) C=CC (=O) C2=C (C=C (C=C2OC) OC) O
Molecular Formula
C18H18O5
Molecular Weight
314.33
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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