Products for Research Use Only

Tariquidar

CAT: 0013-GTR19162829-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19162829-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
A potent, specific P-gp inhibitor with Kd of 5.1 nM; potentiates the cytotoxicity of several drugs including doxorubicin, paclitaxel, etoposide, and vincristine in a panel of human MDR cell lines at 25-80 nM; exhibits potent i.v. and p.o. activity without apparently enhancing the plasma pharmacokinetics of paclitaxel or the toxicity of coadministered drugs.Breast Cancer Phase 2 Discontinued.
CAS Number
206873-63-4
Product Name Alternative
XR 9576 | XR-9576 | XR9576
Purity
>98% (HPLC)
Solubility
DMSO: ≥ 100 mg/mL
Smiles
COC1=CC2=C (CN (CCC3=CC=C (NC (=O) C4=C (NC (=O) C5=CC6=CC=CC=C6N=C5) C=C (OC) C (OC) =C4) C=C3) CC2) C=C1OC |c:17,26,28,31,40,43,49, t:2,4,10,12,22,24,34|
Molecular Formula
C38H38N4O6
Molecular Weight
646.7315
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
3-Quinolinecarboxamide, N-[2-[[[4-[2- (3,4-dihydro-6,7-dimethoxy-2 (1H) -isoquinolinyl) ethyl]phenyl]amino]carbonyl]-4,5-dimethoxyphenyl]-