Products for Research Use Only
RegisterLogin

Tariquidar (dimesylate)

CAT: 0804-HY-10550BSize: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-10550BSize:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Tariquidar dimesylate (XR9576 dimesylate) is a P-glycoprotein (P-gp) inhibitor. Tariquidar dimesylate increases the concentration of the drug in the brain by binding to P-glycoprotein, preventing it from transporting the drug from inside to outside the brain. Tariquidar dimesylate can be used in the study of blood-brain barrier penetration and multidrug resistance[1].
CAS Number
625375-84-0
Product Name Alternative
XR9576 (dimesylate)
UNSPSC
12352005
Target
P-glycoprotein
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease; Others
Assay Protocol
https://www.medchemexpress.com/tariquidar-dimesylate.html
Smiles
O=C(NC1=CC(OC)=C(C=C1C(NC2=CC=C(C=C2)CCN3CC4=C(CC3)C=C(C(OC)=C4)OC)=O)OC)C5=CC6=CC=CC=C6N=C5.OS(=O)(C)=O.OS(=O)(C)=O
Molecular Formula
C38H38N4O6.2CH4O3S.H2O
Molecular Weight
838.94
References & Citations
[1]Tournier N, et al. Complete inhibition of ABCB1 and ABCG2 at the blood–brain barrier by co-infusion of erlotinib and tariquidar to improve brain delivery of the model ABCB1/ABCG2 substrate [11C] erlotinib[J]. Journal of Cerebral Blood Flow & Metabolism, 2021, 41 (7) : 1634-1646.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 3

Related Products

CatalogName
HY-10550-01Tariquidar
HY-10550R-01Tariquidar (Standard)
HY-110377Tariquidar (dihydrochloride)
HY-15666A-01Olverembatinib (dimesylate)
HY-10550A-01Tariquidar (methanesulfonate, hydrate)
HY-109082A-01Cevidoplenib (dimesylate)
HY-13241-01Ralimetinib dimesylate
HY-B0537CPentamidine (dimesylate)
HY-79077-01Osimertinib (dimesylate)
HY-12798A-01Netarsudil (dimesylate)

Alternative Products

CatalogName
MBS5786050Tariquidar dimesylate
202820Tariquidar

Popular Products