Products for Research Use Only
RegisterLogin

SB 525334

CAT: 0013-GTR19162381-01Size: 500 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19162381-01Size:500 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
SB 525334 is a potent and selective inhibitor of TGF-β1 receptor (ALK5) inhibitor with IC50 of 14,5 nM, 4-fold less potent against ALK4 and inactive for ALK2, ALK3, and ALK6 (IC50>10 uM) ; blocks TGFβ1-induced phosphorylation and nuclear translocation of Smad2/3 in renal proximal tubule cells and inhibits TGFβ1-induced increases in PAI-1 and procollagen α1 mRNA expression in A498 renal epithelial carcinoma cells at 1 uM; significantly inhibits PAN-induced proteinuria in rat model of nephritis-induced renal fibrosis.
CAS Number
356559-20-1
Product Name Alternative
SB-525334 | SB525334
Purity
>98% (HPLC)
Solubility
DMSO: ≥ 46 mg/mL
Smiles
CC1=CC=CC (C2=C (C3=CC=C4N=CC=NC4=C3) N=C (C (C) (C) C) N2) =N1
Molecular Formula
C21H21N5
Molecular Weight
343.4249
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Quinoxaline, 6-[2- (1,1-dimethylethyl) -5- (6-methyl-2-pyridinyl) -1H-imidazol-4-yl]-

Related Products

CatalogName
GTR19153626-01SB-269970, SB 269970
GTR19156054-01SB 204990
GTR19160328-01SB-756050
GTR19234665-01SB 206553
GTR19224296-01SB 211475
GTR19218772-01SB-649701
GTR19204834-01SB-277011
GTR19200858-01SB 268262
GTR19200853-01SB 706504
GTR19199673-01SB-429201

Alternative Products

CatalogName
HY-12043-01SB 525334
2880-25SB-525334
2881-5EZSolution™ SB-525334
A10827-200SB 525334 200mg
A10827-100SB 525334 100mg
A10827-25SB 525334 25mg
A10827-10SB 525334 10mg
TBI2983-25MGSB-525334, ALK5
A10827-50SB 525334 50mg
A10827-5SB 525334 5mg

Popular Products