Products for Research Use Only
RegisterLogin

LY2109761

CAT: 0013-GTR19161711-01Size: 500 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19161711-01Size:500 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
A potent, selective and orally active TGF-β RI/II dual inhibitor with Ki of 38/300 nM, respectively; completely inhibits TGF-β-induced Sma2 phosphorylation on tumor cells or the liver microenviroment, inhibits the L3.6pl/GLT soft agar growth, suppresses both basal and TGF-β1-induced cell migration and invasion, and stimulates anoikis in vitro; significantly reduces the tumor burden as well as spontaneous abdominal metastases, and prolongs survival combined with gemicitabine in vivo model of pancreatic cancer.
CAS Number
700874-71-1
Product Name Alternative
LY 2109761 | LY-2109761
Purity
>98% (HPLC)
Solubility
10 mM in DMSO
Smiles
N1 (CCOC2=CC=C3C (C4=C (CCC5) N5N=C4C6=NC=CC=C6) =CC=NC3=C2) CCOCC1
Molecular Formula
C26H27N5O2
Molecular Weight
441.5249
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Quinoline, 4-[5,6-dihydro-2- (2-pyridinyl) -4H-pyrrolo[1,2-b]pyrazol-3-yl]-7-[2- (4-morpholinyl) ethoxy]-

Alternative Products

CatalogName
C08795-200mgLY2109761

Popular Products