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GNF-7

CAT: 0013-GTR19161495-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19161495-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
A potent and selective type-II kinase inhibitor of Bcr-Abl; inhibits wt Bcr-Abl/T315I Bcr-Abl (IC50< 5 nM) and Bcr-Abl mutants such as G250E, Q252H, Y253H, E255K, E255V, F317L, and M351T in biochemical and cellular assays; displays in vivo efficacy against T315I-Bcr-Abl in xenograft mouse model.
CAS Number
839706-07-9
Product Name Alternative
GNF 7 | GNF7
Purity
>98% (HPLC)
Solubility
DMSO: ≥ 33 mg/mL
Smiles
O=C (NC1=CC=C (C) C (N2CC3=CN=C (NC4=CC=C (C) N=C4) N=C3N (C) C2=O) =C1) C5=CC=CC (C (F) (F) F) =C5
Molecular Formula
C28H24F3N7O2
Molecular Weight
547.5311
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Benzamide, N-[3-[1,4-dihydro-1-methyl-7-[ (6-methyl-3-pyridinyl) amino]-2-oxopyrimido[4,5-d]pyrimidin-3 (2H) -yl]-4-methylphenyl]-3- (trifluoromethyl) -

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