Products for Research Use Only

GNF-351

CAT: 0013-GTR19154197-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19154197-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GNF-351 is a potent, pure aryl hydrocarbon receptor (AHR) antagonist (IC50=62 nM) devoid of partial agonist potential; antagonizes agonist and SAhRM-mediated suppression of SAA1, inhibit both DRE-dependent and -independent activity; decreases migration and invasion of HNSCC cells and prevents benzo[a]pyrene-mediated induction of the chemotherapy efflux protein ABCG2.
Purity
>98%
Smiles
N1C2C (=NC (C3=CC (C) =CN=C3) =NC=2NCCC2C3=C (N=C2) C=CC=C3) N (C (C) C) C1
Molecular Formula
C24H25N7
Molecular Weight
411.5
Notes
For research use only.

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