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BG-45

CAT: 0013-GTR19160772-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19160772-01Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
A potent and selective HDAC3 inhibitor with IC50 of 289 nM; shows selectivity over HDAC1 and HDAC2; downregulates phosphorylation (Tyr705 and Ser727) of STAT3 and triggers hyperacetylation of STAT3 in MM cells; significantly enhances bortezomib-induced cytotoxicity; exhibits significant tumor growth inhibition in vivo in a murine xenograft model of human MM.
CAS Number
926259-99-6
Product Name Alternative
BG45
Purity
>98% (HPLC)
Solubility
DMSO: ≥ 48 mg/mL
Smiles
O=C (C1=NC=CN=C1) NC2=CC=CC=C2N
Molecular Formula
C11H10N4O
Molecular Weight
214.2233
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
2-Pyrazinecarboxamide, N- (2-aminophenyl) -

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