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AZ 3146

CAT: 0013-GTR19160549-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19160549-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AZ3146 is a novel and potent Mps1 inhibitor, which was used to probe the role of Mps1's catalytic activity during mitosis. AZ3146 also inhibits FAK, JNK1, JNK2, KSP and Kit. In in vitro kinase assays, AZ3146 inhibited human Mps1Cat with an IC50 (50% inhibitory concentration) of ~35 nM. AZ3146 also efficiently inhibited autophosphorylation of full-length Mps1 immunoprecipitated from human cells.
CAS Number
1124329-14-1
Product Name Alternative
AZ3146 | AZ 3146 | AZ-3146
Purity
>98% (HPLC)
Solubility
DMSO : 11.75 mg/mL 25.96 mM
Smiles
COc1c (Nc2ncc3n (C) c (=O) n (C4CCCC4) c3n2) ccc (OC2CCN (C) CC2) c1
Molecular Formula
C24H32N6O3
Molecular Weight
452.55
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
9-cyclopentyl-2- (2-methoxy-4- (1-methylpiperidin-4-yloxy) phenylamino) -7-methyl-7H-purin-8 (9H) -one

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