Products for Research Use Only

Lycoramine

CAT: 0013-GTR19165195-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19165195-01Size:1 mg
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Description
Lycoramine is a potent acetylcholinesterase (AChE) inhibitor isolated from Lycoris radiata. It is used in research for studying neurodegenerative conditions, with applications in both in vitro enzyme assays and in vivo models of cholinergic dysfunction.
CAS Number
21133-52-8
Product Name Alternative
Radiate, inhibit, Lycoramine, Lycoris, Inhibitor, galanthamine, acetylcholinesterase, AChE, dihydro-derivative, Cholinesterase (ChE)
Field of Research
Neuroscience
Purity
96.19% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.91 mM) ; DMSO:27.5 mg/mL (95.03 mM)
Smiles
[H][C@]12C[C@@H] (O) CC[C@]11CCN (C) Cc3ccc (OC) c (O2) c13
Molecular Formula
C17H23NO3
Molecular Weight
289.37
Storage Conditions
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.

Chemical Information

Lycoramine

Lycoramine is a benzazepine.

CAS Number21133-52-8
PubChem CID443723
IUPAC Name(1R,12S,14S)-9-methoxy-4-methyl-11-oxa-4-azatetracyclo[8.6.1.01,12.06,17]heptadeca-6(17),7,9-trien-14-ol
Molecular FormulaC17H23NO3
Molecular Weight289.4
XLogP2
Topological Polar Surface Area41.9
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count1
Heavy Atom Count21
Formal Charge0
Complexity403
SMILES
CN1CC[C@@]23CC[C@@H](C[C@@H]2OC4=C(C=CC(=C34)C1)OC)O
InChI
InChI=1S/C17H23NO3/c1-18-8-7-17-6-5-12(19)9-14(17)21-16-13(20-2)4-3-11(10-18)15(16)17/h3-4,12,14,19H,5-10H2,1-2H3/t12-,14-,17-/m0/s1
InChIKey
GJRMHIXYLGOZSE-JDFRZJQESA-N
Chemical Structure
2D Structure
2D structure of Lycoramine
CAS: 21133-52-8
CID: 443723
Formula: C17H23NO3
MW: 289.4
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight289.4
XLogP32
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count1
Exact Mass289.16779360
Monoisotopic Mass289.16779360
Topological Polar Surface Area41.9 Ų
Heavy Atom Count21
Formal Charge0
Complexity403
Isotope Atom Count0
Defined Atom Stereocenter Count3
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes