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ISO-1

CAT: 0013-GTR19160318-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0013-GTR19160318-01Size:1 g
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Description
ISO-1, also known as MIF Antagonist and ISO-1 and Macrophage Migration Inhibitory Factor, is a MIF inhibitor. ISO-1 has CAS#478336-92-4. MDK-6924 Protects Photoreceptors and Reduces Gliosis in Experimental Retinal Detachment. Systemic administration of the MIF inhibitor ISO-1 significantly blocked photoreceptor apoptosis, outer nuclear layer (ONL) thinning, and retinal gliosis. ISO-1 and MIF knockout (MIFKO) had greater accumulation of Müller glia pERK expression in the detached retina, suggesting that Müller survival pathways might underlie the neuroprotective response.
CAS Number
478336-92-4
Product Name Alternative
ISO-1 | ISO 1 | ISO1 | MIF Antagonist
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 36 mg/mL; 153.04 mM
Smiles
COC (=O) CC1CC (=NO1) c1ccc (O) cc1
Molecular Formula
C12H13NO4
Molecular Weight
235.2
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
4,5-dihydro-3- (4-hydroxyphenyl) -5-isoxazoleacetic acid, methyl ester

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