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AG1024

CAT: 0013-GTR19158655-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19158655-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AG-1024 is also called Tyrphostin, is a selective inhibitor of IGF-1R. AG-1024 was used to evaluate effects on proliferation, radiosensitivity, and radiation-induced cell apoptosis in a human breast cancer cell line MCF-7. Exposure to Tyrphostin AG 1024 inhibited proliferation and induced apoptosis in a time-dependent manner, and the degree of growth inhibition for IC20 plus irradiation (4 Gy) was up to 50% compared to the control. Tyrphostin AG 1024 could be used as a potential therapeutic agent in combination with irradiation.
CAS Number
65678-07-1
Product Name Alternative
AG1024 | AG-1024 | AG 1024. Tyrphostin
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 50 mg/mL; 163.84 mM
Smiles
CC (C) (C) c1c (c (cc (c1) C=C (C#N) C#N) Br) O
Molecular Formula
C14H13BrN2O
Molecular Weight
305.17
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
2- (3-bromo-5-tert-butyl-4-hydroxybenzylidene) malononitrile

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