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AG1024

CAT: 0931-T2693-06Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0931-T2693-06Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
65678-07-1
Target
Apoptosis, IGF-1R
Related Pathways
Apoptosis, Tyrosine Kinase/Adaptors
Purity
0.9937
Bioactivity
AG1024 (Tyrphostin) suppresses IGF-1R autophosphorylation (IC50=7 μM), and is less potent for IR (IC50=57 μM) .
Smiles
CC(C)(C)c1cc(C=C(C#N)C#N)cc(Br)c1O
Molecular Formula
C14H13BrN2O
Molecular Weight
305.17
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

Tyrphostin AG 1024

2-[(3-bromo-5-tert-butyl-4-hydroxyphenyl)methylidene]propanedinitrile is an alkylbenzene.

CAS Number65678-07-1
PubChem CID2044
IUPAC Name2-[(3-bromo-5-tert-butyl-4-hydroxyphenyl)methylidene]propanedinitrile
Molecular FormulaC14H13BrN2O
Molecular Weight305.17
XLogP4
Topological Polar Surface Area67.8
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count2
Heavy Atom Count18
Formal Charge0
Complexity414
SMILES
CC(C)(C)C1=C(C(=CC(=C1)C=C(C#N)C#N)Br)O
InChI
InChI=1S/C14H13BrN2O/c1-14(2,3)11-5-9(4-10(7-16)8-17)6-12(15)13(11)18/h4-6,18H,1-3H3
InChIKey
ABBADGFSRBWENF-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Tyrphostin AG 1024
CAS: 65678-07-1
CID: 2044
Formula: C14H13BrN2O
MW: 305.17
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight305.17
XLogP34
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count2
Exact Mass304.02113
Monoisotopic Mass304.02113
Topological Polar Surface Area67.8 Ų
Heavy Atom Count18
Formal Charge0
Complexity414
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
MBS3608955-01AG1024
SF5409-5mgAG1024 (IGF-1R inhibitor)

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