RABBIT ANTI HUMAN 5-HT7 RECEPTOR (C-TERMINAL)

• Gene Name:

  [5-HT7]

• NCBI Gene ID:

  3363

• Reactivity:

  Mouse (Expected from Sequence)

• Storage Conditions:

  Store at 4 °C or at -20 °C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
  Shelf Life: 18 months from date of despatch.

• Specificity:

  This item detects an epitope within the C-terminal of the serotonin (5-hydroxytryptamine, 5-HT) receptor 5-HT7, which belongs to the G-protein coupled receptor superfamily. Serotonin is a neurotransmitter and vasoactive amine which is thought to play a role in various cognitive and behavioural functions including pain, appetite, mood and sleep.
  
  Signalling through 5-HT7 has several effects, including regulation of the circadian rhythm and mediation of smooth-muscle relaxation in the vasculature and gastrointestinal tract. Signalling though 5-HT7 has also been shown to contribute to early T-cell activation.
  
  5-HT7 has been implicated in depression, autism, and other neuropsychiatric disorders.

• Other Gene Names:

  [HTR7; HTR7; 5-HT7; 5-HT-7; 5-HT7]

• Short Name:

  [5-HT7 RECEPTOR]

• Other Product Names:

  [5-hydroxytryptamine receptor 7 isoform a; 5-hydroxytryptamine receptor 7; 5-hydroxytryptamine receptor 7; 5-HT-7; 5-HT-X; 5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled); 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled; 5-HT-X; Serotonin receptor 7]

• NCBI GI Number:

  4504547

• NCBI Accession Number:

  NP_000863.1

• NCBI GB Accession Number:

  NM_000872.4

• Uniprot Accession Number:

  P34969

• CAS Number:

  9007-83-4