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RABBIT ANTI HUMAN MDC

CAT: 0544-MBS221724-01Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0544-MBS221724-01Size:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
[MDC]
NCBI Gene ID
6367
Storage Conditions
Prior to reconstitution store at 4 °C. After reconstitution store at -20 °C. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 12 months from date of reconstitution.
Specificity
This item is specific for human MDC (macrophage-derived cytokine), otherwise known as CCL22, a member of the CC chemokine family expressed by macrophages, monocyte-derived dendritic cells, epithelial cells, fibroblasts and highly expressed in the thymus.

MDC acts as a chemoattractant for monocytes, dendritic cells, activated T lymphocytes and NK cells, through binding to chemokine (C-C motif) receptor 4 (CCR4). CCR4 is selectively expressed by Th2 cells and several studies have revealed a link between MDC and another ligand of CCR4, known as activation-regulated chemokine (TARC/CCL17), with Th2-mediated inflammatory disorders such as atopic dermatitis.
Other Gene Names
[CCL22; CCL22; MDC; ABCD-1; SCYA22; STCP-1; DC/B-CK; A-152E5.1; MDC; SCYA22]
Short Name
[MDC]
Other Product Names
[C-C motif chemokine 22; C-C motif chemokine 22; C-C motif chemokine 22; CC chemokine STCP-1; MDC(1-69); macrophage-derived chemokine; small inducible cytokine A22; small inducible cytokine subfamily A (Cys-Cys), member 22; small-inducible cytokine A22; stimulated T cell chemotactic protein 1; stimulated T-cell chemotactic protein 1; chemokine (C-C motif) ligand 22; CC chemokine STCP-1; MDC(1-69); Macrophage-derived chemokine; Small-inducible cytokine A22; Stimulated T-cell chemotactic protein 1Cleaved into the following 3 chains:MDC(3-69); MDC(5-69); MDC(7-69)]
NCBI GI Number
22538804
NCBI Accession Number
NP_002981.2
NCBI GB Accession Number
NM_002990.4
Uniprot Accession Number
O00626

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