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Argireline

CAT: 0013-GTR19157632-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19157632-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Argireline (Acetyl hexapeptide-3) is composed of chains of amino acids known as peptides. Argireline significantly inhibits Ca2+ dependent neurotransmitter release (acetylcholine) at the neuromuscular junction. Argireline has antiwrinkle and anti-aging activity.The incubation of Argireline solution in different concentrations with human embryonic kidney HEK-293 (IC50 of 34.862 μM) and neuroblastoma IMR-32 cells (IC50 of 68.458 μM) ) for 48 h have dose dependent antiproliferative effect. Argireline solution incubated in different concentrations with HSF has a dose-dependent antiproliferative effect on those cells. Cellular proliferation is not effected in Argireline low concentration.Argireline is applied to the aged mice twice daily for 6 weeks. There is an improvement in the histological structure of skin tissue in the aged mice; the amount of type I collagen fibers increased, while that of type III collagen fibers decreased. Argireline could improve the histological structure of skin tissue and rejuvenate the aging skin.
CAS Number
616204-22-9
Product Name Alternative
Acetyl hexapeptide-3
Purity
>98% (HPLC)
Solubility
H2O:8.8 mg/mL (9.90 mM; Need ultrasonic and warming)
Smiles
CC (=O) N[C@@H] (CCC (=O) O) C (=C) N[C@@H] (CCC (=O) O) C (=O) N[C@@H] (CCSC) C (=O) N[C@@H] (CCC (=O) N) C (=O) N[C@@H] (CCCNC (=N) N) C (=O) N[C@@H] (CCCNC (=N) N) C (=O) N
Molecular Formula
C34H60N14O12S
Molecular Weight
888.99
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

Alternative Products

CatalogName
M22308-01Argireline
A22764-100Argireline 100mg
A22764-50Argireline 50mg
FA138103-01Argireline acetate
HY-P0033AArgireline (acetate)
A22764-5Argireline 5mg
A22764-10Argireline 10mg
CSB-DT1690Argireline/Acetyl Hexapeptide-6
O003-100Argireline / DNSP-11 CAS: 616204-22-9

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