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Argireline (acetate)

CAT: 0804-HY-P0033ASize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-P0033ASize:1 Each
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Description
Argireline acetate (Acetyl hexapeptide-3 acetate) is a non-toxic, skin-permeable, antiwrinkle peptide. Argireline acetate significantly inhibits Ca2+ dependent neurotransmitter release (acetylcholine) at the neuromuscular junction. Argireline acetate has antiwrinkle and anti-aging activity[1][2][3].
CAS Number
2484708-86-1
Product Name Alternative
Acetyl hexapeptide-3 (acetate) ; Acetyl hexapeptide-8 (acetate)
UNSPSC
12352209
Target
Calcium Channel
Type
Peptides
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/argireline-acetate.html
Solubility
10 mM in DMSO
Smiles
N=C(N)NCCC[C@@H](C(N)=O)NC([C@H](CCCNC(N)=N)NC([C@H](CCC(N)=O)NC([C@H](CCSC)NC([C@H](CCC(O)=O)NC([C@H](CCC(O)=O)NC(C)=O)=O)=O)=O)=O)=O.CC(O)=O
Molecular Formula
C36H64N14O14S
Molecular Weight
949.04
References & Citations
[1]Blanes-Mira C, et al. A synthetic hexapeptide (Argireline) with antiwrinkle activity. Int J Cosmet Sci. 2002 Oct;24 (5) :303-10.|[2]Grosicki M, et al. The study of cellular cytotoxicity of argireline - an anti-aging peptide. Acta Biochim Pol. 2014;61 (1) :29-32.|[3]Wang Y, et al. The anti-wrinkle efficacy of Argireline. J Cosmet Laser Ther. 2013 Aug;15 (4) :237-41.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
Phase 3