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MOUSE ANTI CLOSTRIDIUM DIFFICILE TOXIN B

CAT: 0544-MBS219588-01Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0544-MBS219588-01Size:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Storage Conditions
Store at 4 °C or at -20 °C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Specificity
This item is specific for Clostridium difficile toxin B. No reaction is observed with toxin A. Clostridium difficile is a gram-positive motile bacterium which is the leading cause of diarrhoea in developed countries. The incidence of disease in humans varies greatly with age, spore density and the administration of antibiotics.

Toxin B (TcdB) is a large exotoxin. Its role in disease is less well understood than that of toxin A, though it seems clear that TcdB contributes to disease. Both toxins modifies the Ras superfamily of small GTPases via glycosylation, inactivating them and leading to the disruption of vital signaling pathways in the cell.
Other Gene Names
[toxB; tcdB]
Short Name
[CLOSTRIDIUM DIFFICILE TOXIN B]
Other Product Names
[Toxin B; Toxin B]
NCBI GI Number
136015
NCBI Accession Number
P18177.3
Uniprot Accession Number
P18177

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