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Levomefolic Acid

CAT: 0013-GTR19157349-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19157349-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Levomefolinic acid is a natural active form of folic acid used at the cellular level for DNA reproduction the cysteine cycle and the regulation of homocysteine among other functions. Levomefolinic acid is used as a treatment and to prevent Folate Deficiency. (In Vitro) :Levomefolic acid (5-MTHF) shows interaction with residues Glu406, Ile 418, Lys417 and Tyr453, of which Lys 417 and Tyr 453 play a strong physiological role in the interaction between S1 and ACE and may act as a potential inhibitor of the S1:ACE2 interaction of the SARS-CoV-2 virus.Levomefolic acid (5-MTHF) (50 nM, 72 h) increases intracellular folate metabolite activity by 7-fold better than folic acid by 2-fold in human lymphoblastoid cell line (LCL), and is a good folic acid supplement.
CAS Number
31690-09-2
Product Name Alternative
5-MTHF
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
H2O:5 mg/mL (10.88 mM) ; DMSO:0.526 mg/mL (1.14 mM)
Smiles
CN1[C@@H] (CNc2ccc (cc2) C (=O) N[C@@H] (CCC (O) =O) C (O) =O) CNc2nc (N) [nH]c (=O) c12
Molecular Formula
C20H25N7O6
Molecular Weight
459.46
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
(4- ((((S) -2-amino-5-methyl-4-oxo-145678-hexahydropteridin-6-yl) methyl) amino) benzoyl) -L-glutamic acid

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