Levomefolic acid-13C5

• UNSPSC Description:

  Levomefolic acid-13C5 is the 13C labeled Levomefolic acid[1]. Levomefolic acid (L-5-MTHF) is an orally active, brain-penetrant natural active form of folic acid and is one of the most widely used folic acid food supplements[2][3].

• Target Antigen:

  DNA/RNA Synthesis; Endogenous Metabolite; Reactive Oxygen Species

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Cell Cycle/DNA Damage;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/levomefolic-acid-13c5.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=[13C](O)[13CH2][13CH2][13C@@H]([13C](O)=O)NC(C1=CC=C(NC[C@@H]2N(C)C3=C(NC(N)=NC3=O)NC2)C=C1)=O

• Molecular Weight:

  464.42

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Manisha Prajapat, et al. Virtual screening and molecular dynamics study of approved drugs as inhibitors of spike protein S1 domain and ACE2 interaction in SARS-CoV-2. J Mol Graph Model. 2020 Dec;101:107716.|[3]Maša Vidmar Golja, et al. Simultaneous quantification of intracellular concentrations of clinically important metabolites of folate-homocysteine cycle by LC-MS/MS. Anal Biochem. 2020 Sep 15;605:113830.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2687960-08-1