Products for Research Use Only
RegisterLogin

KYP-2047

CAT: 0013-GTR19157020-01Size: 200 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19157020-01Size:200 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
KYP-2047 is a very potent, selective Prolyl oligopeptidase (POP) inhibitor.In cell lines, oxidative stress induced a robust aggregation of α-synuclein, and low concentrations of KYP-2047 significantly reduced the number of cells with α-synuclein inclusions while abolishing the colocalization of α-synuclein and PREP. KYP-2047 significantly reduced the amount of aggregated α-synuclein, and it had beneficial effects on cell viability. In the transgenic mice, a 5-day treatment with the PREP inhibitor reduced the amount of α-synuclein immunoreactivity and soluble α-synuclein protein in the brain.
CAS Number
796874-99-2
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 100 mg/mL (294.61 mM)
Smiles
O=C (CCCc1ccccc1) N1CCC[C@H]1C (=O) N1CCC[C@H]1C#N
Molecular Formula
C20H25N3O2
Molecular Weight
339.44
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

Related Products

CatalogName
GTR19184325-01MK-2048
GTR19235300-01GTI 2040
GTR19212186-01CCG-2046
GTR19198287-01AGL 2043
GTR19144436-01SHR-2042
GTR19198450A 204
GTR19211234-01Ro 15-2041
GTR19204931-01Ro-15-2041
GTR19173998-01ML-204
GTR19208672-01GC-204

Alternative Products

CatalogName
BA2979-25KYP-2047
6272/5KYP 2047
HY-100475RKYP-2047 (Standard)
217705Prolyl Endopeptidase Inhibitor III, KYP-2047 ((S) -1- ((S) -1- (4-phenylbutanoyl) -pyrrolidine-2-carbonyl) pyrrolidine-2-carbonitrile, 4-phenylbutanoyl-Lprolyl-2 (S) -cyanopyrrolidine, PREP Inhibitor III, KYP-2047)
BNUM2047-50ZAP70 (Chronic Lymphocytic Leukemia Marker) (ZAP70/2047), 1mg/mL
BNUB2047-500ZAP70 (Chronic Lymphocytic Leukemia Marker) (ZAP70/2047), 0.2mg/mL
TL320336VEph receptor B1 (EPHB1) Human shRNA Lentiviral Particle (Locus ID 2047)
TR320336Eph receptor B1 (EPHB1) Human shRNA Plasmid Kit (Locus ID 2047)
36-3383-20Anti-ZAP70 (Chronic Lymphocytic Leukemia Marker) Monoclonal Antibody (Clone: ZAP70/2047)
SR301428Eph receptor B1 (EPHB1) Human siRNA Oligo Duplex (Locus ID 2047)

Popular Products