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KYP-2047 (Standard)

CAT: 0804-HY-100475RSize: 1 EachDry Ice: NoHazardous: No
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Description
KYP-2047 (Standard) is the analytical standard of KYP-2047. This product is intended for research and analytical applications. KYP-2047 is a potent and BBB-penetrating prolyl-oligopeptidase (POP) inhibitor, with an Ki value of 0.023 nM. KYP-2047 reduces glioblastoma proliferation through angiogenesis and apoptosis modulation[1][2].
CAS Number
796874-99-2
Target
Apoptosis; MDM-2/p53; Prolyl Endopeptidase (PREP) ; Reference Standards
Related Pathways
Apoptosis; Metabolic Enzyme/Protease; Others
Field of Research
Cancer
Smiles
N#C[C@H]1N(C([C@H]2N(C(CCCC3=CC=CC=C3)=O)CCC2)=O)CCC1
Molecular Formula
C20H25N3O2
Molecular Weight
339.43
References & Citations
[1]Jalkanen AJ, et al. Beneficial effect of prolyl oligopeptidase inhibition on spatial memory in young but not in old scopolamine-treated rats. Basic Clin Pharmacol Toxicol. 2007 Feb;100 (2) :132-8.|[2]Scuderi SA, et al. KYP-2047, an Inhibitor of Prolyl-Oligopeptidase, Reduces GlioBlastoma Proliferation through Angiogenesis and Apoptosis Modulation. Cancers (Basel) . 2021 Jul 9;13 (14) :3444.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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