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PLX5622 hemifumarate

CAT: 0013-GTR19154554-01Size: 1 ml x 10 mM (in DMSO)Dry Ice: NoHazardous: No
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CAT#:0013-GTR19154554-01Size:1 ml x 10 mM (in DMSO)
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PLX-5622 hemifumarate is a highly selective brain penetrant and orally active CSF1R inhibitor (IC50=0.016 μM; Ki=5.9 nM) . PLX5622 hemifumarate allows for extended and specific microglial elimination, preceding and during pathology development. PLX5622 hemifumarate demonstrates desirable PK properties in varies animals.
Purity
>98%
Smiles
CC1=CN=C (NC=C2CC3=C (F) N=C (NCC4=CC (F) =CN=C4OC) C=C3) C2=C1.O=C (O) /C=C/C (O) =O.CC5=CN=C (NC=C6CC7=C (F) N=C (NCC8=CC (F) =CN=C8OC) C=C7) C6=C5
Molecular Formula
C23H21F2N5O3
Molecular Weight
453.45
Notes
For research use only.

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