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S-Methylglutathione

CAT: 0804-HY-W009177-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W009177-01Size:5 mg
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Description
S-Methylglutathione is an S-substitued glutathione and a stronger nucleophile than GSH[1]. S-Methylglutathione has inhibitory effect on glyoxalase 1[2].
CAS Number
2922-56-7
UNSPSC
12352209
Hazard Statement
H302, H315, H319, H335
Target
Glyoxalase (GLO)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/s-methylglutathione.html
Concentration
10mM
Purity
99.40
Solubility
H2O : 25 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(O)CNC([C@H](CSC)NC(CC[C@@H](C(O)=O)N)=O)=O
Molecular Formula
C11H19N3O6S
Molecular Weight
321.35
Precautions
H302, H315, H319, H335
References & Citations
[1]Foye WO, et al. Synthesis and evaluation of N-alkanoyl-S-benzyl-L-cysteinylglutamic acid esters as glyoxalase I inhibitors and anticancer agents. J Pharm Sci. 1984 Apr;73 (4) :559-61.|[2]Milos I. Djuran, et al. Reactivity of chloro- and aqua (diethylenetriamine) platinum (II) ions with glutathione, S-methylglutathione, and guanosine 5'-monophosphate in relation to the antitumor activity and toxicity of platinum complexes. Inorg. Chem. 1991, 30, 12, 2648–2652
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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