Products for Research Use Only
RegisterLogin

Tecalcet (Hydrochloride)

CAT: 0804-HY-10167A-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-10167A-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Tecalcet Hydrochloride (R 568 Hydrochloride), an orally active calcimimetic compound, allosterically and positively modulates the calcium-sensing receptor (CaSR) . Tecalcet Hydrochloride (R 568 Hydrochloride) increases the sensitivity to activation by extracellular Ca2+[1][2][3].
CAS Number
177172-49-5
Product Name Alternative
R-568 (hydrochloride) ; NPS R-568
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
CaSR
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/tecalcet-hydrochloride.html
Purity
99.66
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
C[C@@H](NCCCC1=CC=CC=C1Cl)C2=CC=CC(OC)=C2.[H]Cl
Molecular Formula
C18H23Cl2NO
Molecular Weight
340.29
Precautions
H302, H315, H319, H335
References & Citations
[1]Wada, M., et al. The calcimimetic compound NPS R-568 suppresses parathyroid cell proliferation in rats with renal insufficiency. Control of parathyroid cell growth via a calcium receptor. Journal of Clinical Investigation 100 (12), 2977-2983 (1997) .|[2]Nemeth, E.F., et al. The parathyroid calcium receptor: a novel therapeutic target for treating hyperparathyroidism. Pediatr.Nephrol. 10 (3), 275-279 (1996) .|[3]Nemeth, E.F., et al. Calcimimetics with potent and selective activity on the parathyroid calcium receptor. Proceedings of the National Academy of Sciences of the United States of America 95 (7), 4040-4045 (1998) .
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Phase 2

Related Products

CatalogName
HY-10167Tecalcet
HY-B0500BAlverine (hydrochloride)
HY-W714513VU0469650 (hydrochloride)
HY-W708286-01α-Pyrrolidinobutiothiophenone (hydrochloride)
HY-W492795Quifenadine (hydrochloride)
HY-W012179-01Phenylpiperazine (hydrochloride)
HY-Z6449-01Phenylephrone (hydrochloride)
HY-W209279(±) Anabasine (hydrochloride)
HY-W027446-01Pyridoxal hydrochloride
HY-W011963-01Melevodopa (hydrochloride)

Alternative Products

CatalogName
C04298-5mgTecalcet Hydrochloride
A21404-100Tecalcet Hydrochloride 100mg
A21404-5Tecalcet Hydrochloride 5mg
A21404-50Tecalcet Hydrochloride 50mg
A21404-25Tecalcet Hydrochloride 25mg
A21404-10Tecalcet Hydrochloride 10mg
A21404-2Tecalcet Hydrochloride 2mg
A21404-10mM-DTecalcet Hydrochloride 10mM * 1mL in DMSO
MBS3602052-01Tecalcet
328014Tecalcet HCl

Popular Products