Products for Research Use Only

Cys-PKHB1

CAT: 0013-GTR19144551-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19144551-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cys-PKHB1 (Cys-txCD47) is a polypeptide consisting of a cysteine (Cys) residue coupled with PKHB1, which is a CD47 agonist peptide that acts as a thrombospondin-1 peptide mimetic with anti-tumor properties. In breast cancer cells, PKHB1 induces mitochondrial changes, ROS production, intracellular Ca+ accumulation, and calcium-dependent cell death. Additionally, PKHB1 activates the immune system by inducing immunogenic cell death in breast cancer cells.
Field of Research
Immunology & Inflammation
Molecular Weight
1487.88
Storage Conditions
-20°C
Notes
For research use only.