CDK9-IN-10

• Description:

  CDK9-IN-10 is a potent CDK9 inhibitor. CDK9-IN-10 is the ligand for the PROTAC CDK9 degrader-2 (HY-112811) [1].

• UNSPSC:

  12352005

• Target:

  CDK; Ligands for Target Protein for PROTAC

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage; PROTAC

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/cdk9-in-10.html

• Purity:

  98.09

• Solubility:

  DMSO : ≥ 100 mg/mL

• Smiles:

  OC1=C2C(C(C=C(C3=CC=CC=C3)O2)=O)=C(O)C=C1OCC4=CC=CC=C4

• Molecular Formula:

  C22H16O5

• Molecular Weight:

  360.36

• References & Citations:

  [1]Bian J, et al. Discovery of Wogonin-based PROTACs against CDK9 and capable of achieving antitumor activity. Bioorg Chem. 2018 Dec;81:373-381.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture and light)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  CDK9

• CAS Number:

  3542-63-0