Antibacterial agent 180

• UNSPSC Description:

  Antibacterial agent 180 (15g), an appropriate substrate for the type I nitro reductases (TcNTR I), is a promising antitrypanosomatid agent. Antibacterial agent 180 (15g) shows nonmutagenic potential against Salmonella typhimurium strains (TA98, TA100, and TA102)[1].

• Target Antigen:

  Bacterial; Parasite

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/antibacterial-agent-180.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=[N+]([O-])C1=NN(C=N1)CC2=CN(N=N2)C3=CC=C(C=C3)OC(F)(F)F

• Molecular Weight:

  355.23

• References & Citations:

  [1]Bruno I Pelizaro, et al. Design and Synthesis of Novel 3-Nitro-1 H-1,2,4-triazole-1,2,3-triazole-1,4-disubstituted Analogs as Promising Antitrypanosomatid Agents: Evaluation of In Vitro Activity against Chagas Disease and Leishmaniasis. J Med Chem. 2024 Feb 22;67(4):2584-2601.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  9007-83-4