8-Hydroxygenistein

CAT: 0804-HY-W753779Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-W753779Size:1 Each
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Description
8-Hydroxygenistein (8-OHG) is an antioxidant that can effectively scavenge nitric oxide (NO) and superoxide anion (O₂⁻) . 8-Hydroxygenistein belongs to ortho-dihydroxy isoflavones (ODI) and is abundantly present in dark soy sauce and light soy sauce. Its antioxidant activity is stronger than that of its parent compound genistein (HY-14596) . The content of 8-Hydroxygenistein is positively correlated with the antioxidant capacity of soy sauce (r = 0.959), and it remains highly stable even after being heated in boiling water for 60 minutes. During the brewing and storage of soy sauce, 8-Hydroxygenistein effectively prevents oxidative damage, making it promising for use in food antioxidant research.
CAS Number
[13539-27-0]
Product Name Alternative
8-OHG
UNSPSC
12352005
Target
NO Synthase; Reactive Oxygen Species (ROS)
Type
Natural Products
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/8-hydroxygenistein.html
Smiles
O=C1C(C2=CC=C(O)C=C2)=COC3=C1C(O)=CC(O)=C3O
Molecular Formula
C15H10O6
Molecular Weight
286.24
References & Citations
[1]Esaki H, et al. Potent antioxidative o-dihydroxyisoflavones in soy sauces and their antioxidative activities[J]. 2002.|[2]Shao J, et al. Synthesis, characterization, and antioxidant activity of 8-hydroxygenistein[J]. Natural Product Communications, 2020, 15 (1) : 1934578X20901399.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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