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2′-Hydroxygenistein

CAT: 0804-HY-N1735-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N1735-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
2′-Hydroxygenistein is a natural product that can be isolated from Crotalaria pallida and C. assamica. 2′-Hydroxygenistein shows anti-inflammatory activity. 2′-Hydroxygenistein shows significant concentration-dependent inhibitory effects on the release of β-glucuronidase and lysozyme from rat neutrophils, with IC50 values of 5.9 ± 1.4 and 9.7 ± 3.5 μM, respectively[1].
CAS Number
1156-78-1
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Bacterial; β-glucuronidase
Type
Natural Products
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/2-hydroxygenistein.html
Purity
99.41
Solubility
10 mM in DMSO
Smiles
O=C1C(C2=CC=C(O)C=C2O)=COC3=CC(O)=CC(O)=C13
Molecular Formula
C15H10O6
Molecular Weight
286.24
Precautions
H302, H315, H319, H335
References & Citations
[1]Ko HH, Weng JR, Tsao LT, Yen MH, Wang JP, Lin CN. Anti-inflammatory flavonoids and pterocarpanoid from Crotalaria pallida and C. assamica. Bioorg Med Chem Lett. 2004 Feb 23;14 (4) :1011-4.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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