Sodium orthovanadate

CAT: 0804-HY-D0852-01Size: 500 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-D0852-01Size:500 mg

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Description

Sodium orthovanadate is an inhibitor of protein tyrosine phosphatases, alkaline phosphatases and a number of ATPases, most likely acting as a phosphate analogue.

CAS Number

13721-39-6

UNSPSC

12352200

Hazard Statement

H302+H312+H332, H315, H319

Target

Phosphatase

Type

Biochemical Assay Reagents

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/Sodium-orthovanadate.html

Purity

99.00

Solubility

DMSO : < 1 mg/mL (ultrasonic; warming; heat to 80°C) |H2O : 8 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

[O].[Na].[V]

Molecular Formula

Na3O4V

Molecular Weight

183.91

Precautions

H302+H312+H332, H315, H319

References & Citations

[1]Gordon JA, et al. Use of vanadate as protein-phosphotyrosine phosphatase inhibitor. Methods Enzymol. 1991;201:477-82.|[2]Wu DN, et al. Down-regulation of PTEN by sodium orthovanadate inhibits ASK1 activation via PI3-K/Akt during cerebral ischemia in rat hippocampus. Neurosci Lett. 2006 Aug 14;404 (1-2) :98-102.

Shipping Conditions

Room Temperature

Storage Conditions

Store at room temperature, keep dry and cool

Scientific Category

Biochemical Assay Reagents

Clinical Information

No Development Reported

Chemical Information

Sodium orthovanadate

Trisodium vanadate is an inorganic sodium salt of formula Na3VO4 containing the tetrahedral VO43. It has a role as an EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor, an antineoplastic agent, a radiation protective agent and an apoptosis inducer. It contains a vanadate(3-).

CAS Number	13721-39-6
PubChem CID	61671
IUPAC Name	trisodium;trioxido(oxo)vanadium
Molecular Formula	Na3O4V
Molecular Weight	183.908
Topological Polar Surface Area	86.3
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	0
Heavy Atom Count	8
Formal Charge	0
Complexity	36

SMILES

[O-][V](=O)([O-])[O-].[Na+].[Na+].[Na+]

InChI

InChI=1S/3Na.4O.V/q3*+1;;3*-1;

InChIKey

IHIXIJGXTJIKRB-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 13721-39-6

CID: 61671

Formula: Na3O4V

MW: 183.908

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	183.908
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	0
Exact Mass	183.892924
Monoisotopic Mass	183.892924
Topological Polar Surface Area	86.3 Å²
Heavy Atom Count	8
Formal Charge	0
Complexity	36.8
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	4
Compound Is Canonicalized	Yes

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Alternative Products

Catalog	Name
TRC-S655003-250G	Sodium Orthovanadate

Sodium orthovanadate

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