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Lomustine (Standard)

CAT: 0804-HY-13669R-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-13669R-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Lomustine (Standard) is the analytical standard of Lomustine. This product is intended for research and analytical applications. Lomustine (CCNU; NSC 79037) is a DNA alkylating agent, with antitumor activity.
CAS Number
13010-47-4
Product Name Alternative
CCNU (Standard) ; NSC 79037 (Standard)
UNSPSC
12352211
Target
Apoptosis; Autophagy; DNA Alkylator/Crosslinker; Reference Standards
Type
Reference Standards
Related Pathways
Apoptosis; Autophagy; Cell Cycle/DNA Damage; Others
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/lomustine-standard.html
Purity
99.94
Smiles
O=C(NC1CCCCC1)N(CCCl)N=O
Molecular Formula
C9H16ClN3O2
Molecular Weight
233.70
References & Citations
[1]Wang P, et al. Oncometabolite D-2-Hydroxyglutarate Inhibits ALKBH DNA Repair Enzymes and Sensitizes IDH Mutant Cells to Alkylating Agents. Cell Rep. 2015 Dec 22;13 (11) :2353-2361.|[2]Harvey KA, et al. Enhanced anticancer properties of lomustine in conjunction with docosahexaenoic acid in glioblastoma cell lines. J Neurosurg. 2015 Mar;122 (3) :547-56.|[3]Yagiz K, et al. Toca 511 plus 5-fluorocytosine in combination with lomustine shows chemotoxic and immunotherapeutic activity with no additive toxicity in rodent glioblastoma models. Neuro Oncol. 2016 Oct;18 (10) :1390-401.
Shipping Conditions
Room Temperature
Storage Conditions
4°C, sealed storage, away from light and moisture
Scientific Category
Reference Standards
Clinical Information
Launched

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