PHGDH-inactive

• UNSPSC Description:

  PHGDH-inactive has no activity against PHGDH and serves as a negative control of NCT-502 and NCT-503[1].

• Target Antigen:

  Phosphoglycerate Dehydrogenase (PHGDH)

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/phgdh-inactive.html

• Purity:

  99.93

• Solubility:

  DMSO : 83.33 mg/mL (ultrasonic)

• Smiles:

  S=C(NC1=NC(C)=CC(C)=C1)N2CCN(CC2)C3=CC=NC=C3

• Molecular Weight:

  327.45

• References & Citations:

  [1]Pacold ME, et al. A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate [published correction appears in Nat Chem Biol. 2016 Jul 19;12 (8):656]. Nat Chem Biol. 2016;12(6):452-458.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Clinical Information:

  No Development Reported

• CAS Number:

  1914971-16-6