HMBPP (lithium)

• UNSPSC Description:

  HMBPP (lithium) is an activator for human Vγ9/Vδ2 T cells. HMBPP exhibits phagostimulant property in mosquitos[1][2].

• Target Antigen:

  Nuclear Factor of activated T Cells (NFAT)

• Type:

  Natural Products

• Related Pathways:

  Immunology/Inflammation

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/hmbpp.html

• Purity:

  95.0

• Solubility:

  10 mM in DMSO

• Smiles:

  O=P(OP(O[Li])(O[Li])=O)(O[Li])OC/C=C(C)/CO

• Molecular Weight:

  279.89

• References & Citations:

  [1]Hintz M, et al., Identification of (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate as a major activator for human gammadelta T cells in Escherichia coli. FEBS Lett. 2001 Dec 7;509(2):317-22.|[2]Stromsky VE, et al., Plasmodium metabolite HMBPP stimulates feeding of main mosquito vectors on blood and artificial toxic sources. Commun Biol. 2021 Oct 7;4(1):1161.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, sealed storage, away from moisture and light)

• Clinical Information:

  No Development Reported

• CAS Number:

  396726-03-7