HMBPP (lithium)

HMBPP (lithium)

• CAS Number: 396726-03-7
• UNSPSC Description: HMBPP (lithium) is an activator for human Vγ9/Vδ2 T cells. HMBPP exhibits phagostimulant property in mosquitos[1][2].
• Target Antigen: Nuclear Factor of activated T Cells (NFAT)
• Type: Natural Products
• Related Pathways: Immunology/Inflammation
• Applications: COVID-19-immunoregulation
• Field of Research: Infection; Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/hmbpp.html
• Purity: 95.0
• Solubility: 10 mM in DMSO
• Smiles: O=P(OP(O[Li])(O[Li])=O)(O[Li])OC/C=C(C)/CO
• Molecular Weight: 279.89
• References & Citations: [1]Hintz M, et al., Identification of (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate as a major activator for human gammadelta T cells in Escherichia coli. FEBS Lett. 2001 Dec 7;509(2):317-22.|[2]Stromsky VE, et al., Plasmodium metabolite HMBPP stimulates feeding of main mosquito vectors on blood and artificial toxic sources. Commun Biol. 2021 Oct 7;4(1):1161.
• Shipping Conditions: Blue Ice
• Storage Conditions: -20°C (Powder, sealed storage, away from moisture and light)
• Clinical Information: No Development Reported