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Recombinant Rat CDNF protein

CAT: 0772-CD00137Size: 5 µgDry Ice: NoHazardous: No
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CAT#:0772-CD00137Size:5 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Cerebral dopamine neurotrophic factor (CDNF), also known as ARMET-like protein 1, is encoded by the CDNF gene and widely expressed in neuronal and non-neuronal tissues. The CDNF is a novel neurotrophic factor with strong trophic activity on dopaminergic neurons comparable to that of glial cell line-derived neurotrophic factor (GDNF). Furthermore, it also prevents the 6-hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. By research, CDNF might be beneficial for the treatment of Parkinsons disease. Recombinant rat CDNF contains 163 amino acid residues and it shares 84 % and 87 % a.a. sequence identity with human and Mouse CDNF.
CAS Number
9000-83-3
Molecular Weight
Approximately 18.8 kDa, a single non-glycosylated polypeptide chain containing 163 amino acids.

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