Products for Research Use Only
RegisterLogin

µ-Conotoxin KIIIA (TFA)

CAT: 0804-HY-P5141A-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-P5141A-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
UNSPSC Description
μ-Conotoxin KIIIA TFA is an analgesic μ-conotoxin that can be isolated from Conus kinoshitai. μ-Conotoxin KIIIA blocks mammalian neuronal voltage-gated sodium channels (VGSCs) (Nav1.2). μ-Conotoxin KIIIA TFA can be used for research of pain[1][2].
Target Antigen
Sodium Channel
Type
Peptides
Related Pathways
Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Purity
99.20
Solubility
H2O : 100 mg/mL (ultrasonic)
Smiles
O=C([C@@H](N)CSSC[C@H](NC1=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H]2CCCNC(N)=N)=O)CO)=O)CC3=CNC=N3)=O)CC(O)=O)=O)CCCNC(N)=N)=O)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H]1CC4=CNC5=CC=CC=C45)=O)CCCCN)=O)CO)=O)CO)=O)CSSC[C@H](NC6=O)C(N)=O)=O)CC(N)=O)=O)CSSC[C@@H]6NC2=O.O=C(O)C(F)(F)F.[x]
Molecular Weight
1884.16 (free base)
References & Citations
[1]Khoo KK,et al. Structure of the analgesic mu-conotoxin KIIIA and effects on the structure and function of disulfide deletion. Biochemistry. 2009 Feb 17;48(6):1210-9.|[2]Pan X, Li Z, et al. Molecular basis for pore blockade of human Na+ channel Nav1.2 by the μ-conotoxin KIIIA. Science. 2019 Mar 22;363(6433):1309-1313.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Clinical Information
No Development Reported

Related Products

CatalogName
HY-P5141µ-Conotoxin KIIIA
HY-P1268A-01α-Conotoxin PIA (TFA)
HY-P0189A-01ω-Conotoxin GVIA (TFA)
HY-P1365Aα-Conotoxin MII (TFA)
HY-P1267A-01α-Conotoxin PnIA (TFA)
HY-P1269A-01α-Conotoxin AuIB (TFA)
HY-P0188A-01ω-Conotoxin MVIIC (TFA)
HY-125777A-01α-Conotoxin Vc1.1 (TFA)
HY-P5808A-01Iota-conotoxin RXIA (TFA)
HY-P5858µ-Conotoxin SIIIA

Alternative Products

CatalogName
CON025-01000µ-conotoxin KIIIA
T80159-01μ-Conotoxin KIIIA
MBS5821818u-Conotoxin KIIIA
MBS1255673-01Recombinant Conus kinoshitai Mu-conotoxin KIIIA
C8683-5α-Conotoxin AuIB TFA
T75927-01α-Conotoxin MII TFA
T75876-01α-Conotoxin PIA TFA
T75875-01α-Conotoxin PnIA TFA
T75727-01ω-Conotoxin GVIA TFA
T75726ω-Conotoxin MVIIC TFA

Popular Products