α-Conotoxin PIA (TFA)

α-Conotoxin PIA (TFA)

• UNSPSC Description: α-Conotoxin PIA TFA is a nicotinic acetylcholine receptor (nAChR) antagonist that targets nAChR subtypes containing α6 and α3 subunits. α-Conotoxin PIA has the potential for the research of Parkinson’s disease, and schizophrenia[1]。
• Target Antigen: nAChR
• Type: Peptides
• Related Pathways: Membrane Transporter/Ion Channel;Neuronal Signaling
• Applications: Neuroscience-Neurodegeneration
• Field of Research: Neurological Disease
• Purity: 99.81
• Solubility: DMSO : ≥ 250 mg/mL
• Smiles: O=C(N[C@@H](CC(O)=O)C(N1[C@@H](CCC1)C(N[C@@H](CSSC[C@@H](C(N[C@@H]([C@H](O)C)C(N[C@@H](C(C)C)C(N[C@@H](CC2=CNC=N2)C(N[C@@H](CC(N)=O)C(N3[C@@H](CCC3)C(N[C@@H](CCC(N)=O)C(N[C@H]4[C@@H](C)CC)=O)=O)=O)=O)=O)=O)=O)NC5=O)C(N[C@@H](CSSC[C@@H](C(N)=O)NC4=O)C(N[C@@H](CO)C(N[C@@H](CC(N)=O)C(N6[C@@H](CCC6)C(N[C@H]5C(C)C)=O)=O)=O)=O)=O)=O)=O)[C@H](CCCNC(N)=N)N.FC(C(O)=O)(F)F
• Molecular Weight: 2323.33
• References & Citations: [1]Seung-Wook Chi , et al. Solution Structure of Alpha-Conotoxin PIA, a Novel Antagonist of alpha6 Subunit Containing Nicotinic Acetylcholine Receptors. Biochem Biophys Res Commun. 2005 Dec 30;338(4):1990-7.
• Shipping Conditions: Blue Ice
• Storage Conditions: -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
• Clinical Information: No Development Reported